Combined effects of in utero and adolescent tobacco smoke exposure on lung function in C57Bl/6J mice

Foetal determinants of airway function, such as in utero exposure to maternal cigarette smoke (CS), may create a predisposition to adult airflow obstruction and COPD in adulthood. It has been suggested that active smoking in adolescence and pre-existing airflow obstruction have synergistic deleterious effects.

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